Catalysis
Palladium catalysts
1st and 2nd Generations of Catalysts
NOVECAT G1-01
NOVECAT G1-02
NOVECAT G2-01
NOVECAT G2-03
|
Ar1-X |
(HOB)2-Ar2 |
Ar1-Ar2 |
Cat. |
Pd |
Yield |
[Pd]* |
 |
 |
 |
G1-01 |
0.001 |
93 |
<2 |
 |
|
|
G1-01 |
0.01 |
89 |
<2 |
 |
|
|
G2-03 |
1 |
94 |
|
 |
|
|
G2-03 |
0.2 |
99 |
|
 |
|
|
G2-03 |
0.5 |
88 |
31 |
 |
|
|
G2-03 |
0.5 |
95 |
|
 |
|
|
G2-03 |
1 |
96 |
* : [Pd]Prod (ppm)
3rd Generation of Catalysts
NOVECAT G3-01
|
Ar1-X |
HNR1R2 |
Ar1-NR1R2 |
Solvent |
Pd (mol%) |
T (°C) |
Yield (%) |
[Pd]* |
 |
 |
 |
Dioxane |
0.1 |
80 |
>99 |
25 |
|
|
|
Dioxane |
0.05 |
98 |
95 |
|
|
|
|
MeTHF |
0.1 |
80 |
>99 |
24 |
|
|
|
CPME |
0.1 |
80 |
93 |
38 |
|
|
|
MeCyclohexane |
0.1 |
80 |
74 |
|
|
|
|
Dioxane |
0.1 |
98 |
95 |
|
|
|
|
Dioxane |
0.5 |
98 |
>99 |
|
|
|
|
Dioxane |
1 |
98 |
91 |
|
 |
|
|
CPME |
0.2 |
100 |
96 |
8 |
* : [Pd]Prod (ppm)
4th Generation of Catalysts
NOVECAT G4-02
Technology
- Excellent efficiency with low catalyst amount
- Easy to eliminate (filterable) with low leaching
- Efficient in concentrated media (0.5M/substrate)
- High and reproducible metal content inside catalysts
NOVECAL propose (lien vers Imidazole and imidazolium salts a range of imidazole and imidazolium to be introduced on supports or (macro)molecules by simple reactions (nucleophilic substitutions, click chemistry, surface functionalization, …). Such precursor leads to efficient PEPPSI like transition metal - NHC complexes.
Scope of PEPPSI like carbene precursors for easy functionalization on supports
